Seminar: Identification of novel sirtuin regulators by virtual screening

  • Date: –14:30
  • Location: Biomedicinskt centrum, BMC roomB7:111a
  • Lecturer: Maija Lahtela-Kakkonen,University of Eastern Finland, Kuopio
  • Organiser: department of Pharmacy
  • Contact person: Per Larsson
  • Seminarium

Epigenetics has important function in the development of age-related diseases such as cancer.1,2 Acetylation/deacetylation of chromatin-interacting proteins is central to the epigenetic regulation of genome architecture and gene expression. Among the most promising epigenetic targets in drug development for age-related diseases is considered one family of anti-aging genes, the sirtuins. Sirtuins a